LM10 Benchtop

LM10 Benchtop

How LM10 Microfluidizer Works

The LM10 Microfluidizer® processor features an economical air-driven intensifier pump that supplies the desired pressure at a constant rate to the product stream. The pump travels through it's pressure stroke, driving the product at a constant pressure through precisely defined fixed-geometry microchannels within the interaction chamber. The product stream accelerates to high velocities, creating shear rates within the product stream that are orders of magnitude greater than any other conventional means. The entire product experiences identical processing conditions, producing the desired results, including uniform product and droplet size reduction (often submicron), deagglomeration and high-yield cell disruption. 

Recommended High Pressure Homogenizer Uses

The LM10 high-pressure laboratory homogenizer is recommended for small sample processing in the following applications:

  • Emulsions
  • Dispersions
  • Liposomes
  • Cell Disruption

Unique Benefits

The LM10 Microfluidizer® processor:

  • Operates at pressures up to 23,000 psi (1546 bar)
  • Requires a minimum sample size of 14 ml
  • Achieves unmatched particle size reduction/disruption performance at low process pressure, which limits sample temperature rise during processing
  • Attains higher product yields after sterile filtration with tighter particle size distribution
  • Promotes optimal temperature control through the removable cooling coil and cooling bath
  • Saves on development time in pilot/production with linear volumetric scaleup
  • Enhances repeatability with easy-to-use digital pressure control
  • Improves experimental reliability with real-time temperature monitoring
  • Ensures dependable process performance over time with maintenance reminder and operator alerts
  • Adapts to future experimentation possibilities with field-upgradable firmware

Standard Features

  • 300 ml glass reservoir
  • Ceramic interaction chamber assembly
  • Cooling coil and chilled bath assembly
  • Thermocouple at product outlet
  • Easily autoclavable
  • Easy-to-use color touchscreen control interface

Optional Features

  • Diamond interaction chamber
  • Process pressure transducer
  • Larger capacity glass or stainless steel reservoirs
  • Thermocouple at product inlet
  • Process fluid recirculation assembly/kit
  • Gasket materials