Full dissolution software solution

The ERWEKA Disso.NET software is the perfect companion for our semi-automated dissolution HPLC On-/Offline systems. The software takes over full control and offers support for all test methods, that can be applied with the dissolution system with HPLC analysis.

Disso.NET helps you with standard dissolution jobs, handles qualification tasks and provides control over each single function of the connected devices (e.g. DT, PVP and auto sampler). In addition, the software includes an easy to handle method editor for comfortable programming of dissolution methods (for highest safety in GMP environment). Our audit trail also generates detailed protocols of all events and times and thus enables tracing changes at any time. After finishing the dissolution test, Disso.NET creates comprehensive reports (as PDF-files or printouts) and can export all results in various formats (e. g. as XML file).

HPLC Sampler

Reliable and flexible collection of samples

With the HPLC sampler samples can be collected and stored reliably and flexibly for subsequent HPLC analysis. It excels through its mechanical precision and its compact design. In addition, the open and modular unit design enables the exchange of single components within a short period of time.

If required, the collected samples can be diluted or stored temporarily cooled and UV-protected for later analysis. The HPLC sampler automatically detects the correct position of the injection syringe, thus ensuring a quick, reproducible injection of the samples into the vials. In this way, potential mixing of the individual samples can be avoided.

The sampler is easily controlled by our ERWEKA Disso.NET software.

Automatic Filter Changer AFC 825

Media replacement with membrane filters

We recommend the implementation of a second filtration to avoid contamination or damage of the HPLC column due to particles, thus improving the accuracy of the HPLC analysis. In combination with the high-precision, practically maintenance-free PVP pump, we offer an additional device: the automated filter changer AFC 825.

The AFC 825 enables the automatic exchange of the used membrane filters (e. g. 0.22 μm, 0.45 μm) after each sampling or each test run. In addition, the media replacement can be conducted via the integrated bypass. As most of the filters are uni-directional - i.e. media is pumped in only one direction - the bypass prevents the media from being pressed back through the used membrane filters, thus avoiding the risk of filter damage

The automated filter changer features a magazine with eight positions for membrane filters (max. 8x25 filter) and comes in two configurations:

• AFC 825 with 12 valves for 6 stations
• AFC 825 with 16 valves for 8 stations