Product Information

The BioFlo 510 is a compact sterilizable-in-place fermentation system ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements.

Gas flow

• Various combinations of one, two, three or four TMFCs:
  • 0.06  –   3 SLPM
  • 0.3  –   15 SLPM
  • 0.6  –   32 SLPM
  • 1  –   64 SLPM
• Overlay (valve only)

Exhaust line

• Exhaust condenser
• Manual or automatic pressure control

Impellers

• Rushton-type – Used commonly for robust cell lines such as bacteria, yeasts, and algae, where maximum OTR is desired. Provided as standard on BioFlo 510 fermentors
• Pitched-blade – Commonly used with mammalian, insect or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial and radial mixing.
• Marine – Commonly used with mammalian, insect, or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial mixing

Sensors

• Single or redundant pH/DO
• Redox
• Foam/level

Addition and sampling

• Resterilizable sampling valve
• Resterilizable addition valves (4 max)
• Resterilizable addition/harvest valve with dip tube (2 max)
• 1.5 in sanitary fitting 7-port septum
• Addition vessels (glass/stainless steel)
• Sterile sampling assembly

Validation

• Basic Package
• Basic Plus Package
• Enhanced Package

Utility regulator & pre-filter kits

• Process air pre-filter/regulator kit
• Instrument air pre-filter/regulator kit
• Water pre-filter/regulator kit
• Process steam regulator kit
• Utility steam pre-filter/regulator kit
• Utility connection kit

Additional options

• Allen Bradley^® CompactLogix™ PLC Control System
• Sprayballs for clean-in-place of vessel› External variable-speed pumps
• External scales› Spare parts kits
• Preventive maintenance kits
• Mobile table
• System passivation
• Glycol/chiller heat exchanger